alexa Targeting telomerase for cancer therapeutics.


Journal of Cancer Science & Therapy

Author(s): Shay JW, Keith WN

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Abstract One of the hallmarks of advanced malignancies is continuous cell growth and this almost universally correlates with the reactivation of telomerase. Although there is still much we do not understand about the regulation of telomerase, it remains a very attractive and novel target for cancer therapeutics. Several clinical trials have been initiated, and in this review we highlight some of the most promising approaches and conclude by speculating on the role of telomerase in cancer stem cells.
This article was published in Br J Cancer and referenced in Journal of Cancer Science & Therapy

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