alexa Thalamic paraventricular nucleus neurons collateralize to innervate the prefrontal cortex and nucleus accumbens.


Journal of Addiction Research & Therapy

Author(s): Bubser M, Deutch AY

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Abstract The prefrontal cortex and nucleus accumbens are primary recipients of medial thalamic inputs, prominently including projections from the thalamic paraventricular nucleus. It is not known if paraventricular neurons collateralize to innervate both the prefrontal cortex and nucleus accumbens. We used dual retrograde tract tracing methods to examine this question. A small population of paraventricular neurons was found to innervate the prefrontal cortex and medial nucleus accumbens. These data suggest that the thalamic paraventricular nucleus may coordinately influence activity in the prefrontal cortex and ventral striatum. Copyright 1998 Elsevier Science B.V.
This article was published in Brain Res and referenced in Journal of Addiction Research & Therapy

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