Author(s): Nicolaou KC, Vourloumis D, Winssinger N, Baran PS, Nicolaou KC, Vourloumis D, Winssinger N, Baran PS
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Abstract A new millenium has begun-grounds enough to question the present state of the total synthesis of natural products. In this review we answer this question by tracing the evolution of this fine art and science from its birth to the present time. This retrospective on total synthesis should serve to demonstrate how far we have come, yet show that the science of total synthesis is still in its infancy.
This article was published in Angew Chem Int Ed Engl
and referenced in Journal of Pharmacognosy & Natural Products