alexa The cell cycle and Myc intersect with mechanisms that regulate pluripotency and reprogramming.
General Science

General Science

Journal of Biotechnology & Biomaterials

Author(s): Singh AM, Dalton S

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Abstract Pluripotent stem cells have long-term proliferative capacity and an unusual mode of cell-cycle regulation and can divide independently of extrinsic mitogenic signals. The last few years has seen evidence emerge that links cell-cycle regulation to the maintenance and establishment of pluripotency. Myc transcription factors appear to be central to this regulation. This review addresses these links and discusses how cell-cycle controls and Myc impact on the maintenance and establishment of pluripotency.
This article was published in Cell Stem Cell and referenced in Journal of Biotechnology & Biomaterials

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