alexa The development of boronic acids as sensors and separation tools.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Journal of Glycomics & Lipidomics

Author(s): Fossey JS, DHooge F, van den Elsen JM, Pereira Morais MP, Pascu SI,

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Abstract Synthetic receptors for diols that incorporate boronic acid motifs have been developed as new sensors and separation tools. Utilizing the reversible interactions of diols with boronic acids to form boronic esters under new binding regimes has provided new hydrogel constructs that have found use as dye-displacement sensors and electrophoretic separation tools; similarly, molecular boronic-acid-containing chemosensors were constructed that offer applications in the sensing of diols. This review provides a somewhat-personal perspective of developments in boronic-acid-mediated sensing and separation, placed in the context of the seminal works of others in the area, as well as offering a concise summary of the contributions of the co-authors in the area. Copyright © 2012 The Japan Chemical Journal Forum and Wiley Periodicals, Inc. This article was published in Chem Rec and referenced in Journal of Glycomics & Lipidomics

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