alexa The effect of copper on the distribution of elements in human spermatozoa.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Maynard PV, Elstein M, Chandler JA

Abstract Share this page

Abstract Examination of intact individual human spermatozoa by X-ray microanalysis revealed that there was a correlation between particular elements in differnt regions of the cell. There was a constancy in the ratios of sodium to potassium in the head and mid-piece and of calcium to phosphorus in the mid-piece in any one sample, though the ratios varied between samples. This may have reflected the external environment since immersion in culture medium or cervical mucus had little effect on motility, yet markedly altered the sodium: potassium ratio. Incubation with copper wire in semen or cervical mucus significantly reduced the subcellular levels of both sodium and potassium inspermatozoa but did not affect the ratio between these two elements. The metal also displaced zinc from the head region, possible replacing it by copper. This may account for the decreased motility of spermatozoa in contact with copper ions. The observed toxicity of copper for human sperm cells lends support to the theory that part ofthe mode of action of the copper IUD may be due to an alteration in sperm fertilizing potential. Although the level of copper released by IUDs containing 200 mm-2 ofcopper wire exerted a minor toxic effect on spermatozoa, the elemental changes observed here may have great significance in the development of more efficient copper-releasing IUDs or an intracervical device whose action would depend on its spermatotoxiceffect.
This article was published in J Reprod Fertil and referenced in Journal of Nanomedicine & Nanotechnology

Relevant Expert PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords