alexa The effect of dietary fat on diet selection may involve central serotonin.
Agri and Aquaculture

Agri and Aquaculture

Journal of Aquaculture Research & Development

Author(s): Mullen BJ, Martin RJ

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Abstract Rats consuming a diet of 34\% tallow select more protein and less carbohydrate than rats fed either 5\% corn oil or tallow or 34\% corn oil (25). To examine potential mechanism(s) of this phenomenon, we fed rats diets containing either tallow or corn oil at levels of 5 or 34\% for 2 days. Sera were analyzed, and rats fed 34\% tallow had higher serum insulin compared with those fed 34\% corn oil. In a second experiment, rats were fed either 34\% corn oil or tallow for 2 days. Brain tissues were analyzed, and rats fed 34\% tallow had elevated serotonin in the raphe area compared with those fed 34\% corn oil. In a third experiment, rats were fed either 34\% corn oil or tallow for 2 days and then given dl-fenfluramine before diet selection. Fenfluramine depressed food intake to a greater degree in rats fed 34\% tallow compared with those fed corn oil. These findings suggest that the diet selection behavior observed in tallow-fed rats may be mediated by a central serotonin system.
This article was published in Am J Physiol and referenced in Journal of Aquaculture Research & Development

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