Author(s): Arshavsky VY, Dizhoor AM, Shestakova IK, Philippov P
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Abstract ATP quenches light-dependent phosphodiesterase (PDE) activation in rod outer segments presumably due to rhodopsin phosphorylation. Here we compared the efficiency of phosphorylated and non-phosphorylated rhodopsins as PDE activators in a reconstituted cell-free system. It is shown that the ability of phosphorylated membranes to activate this enzyme is suppressed compared with non-phosphorylated ones.
This article was published in FEBS Lett
and referenced in Journal of Computer Science & Systems Biology