alexa The effects of atrial fibrillation on myocardial blood flow and energetics


Angiology: Open Access

Author(s): Friedman HS

Abstract Share this page

The changes produced by atrial fibrillation on myocardial blood flow and energetics are unclear. Accordingly, the effects of atrial fibrillation on myocardial blood flow and oxygen consumption were studied in 18 anesthetized dogs. With atrial fibrillation cardiac output and mean aortic pressure declined. Although average myocardial blood flow and oxygen consumption did not change, the alterations in these variables correlated strongly (r = 0.95, P less than 0.01). Moreover, myocardial blood flow changes correlated with those of tension time index and peak dp/dt (r = 0.64, P less than 0.05). Distribution of left ventricular regional flow remained uniform irrespective of the directional changes in blood flow. However, average left ventricular inner to outer wall flow ratio declined and myocardial oxygen extraction increased. Thus, with atrial fibrillation, myocardial blood flow does not change in a consistent fashion, although myocardial blood flow still reflects myocardial oxygen demand. Relative hypoperfusion of subendocardium and an increase in myocardial oxygen extraction suggest that with atrial fibrillation the myocardial blood flow response is abnormal.

  • To read the full article Visit
  • Open Access
This article was published in Proc Soc Exp Biol Med and referenced in Angiology: Open Access

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

  • International Conference on Angiology
    Oct 16-17, 2017, Budapest, Hungary
  • 21st International Conference on Clinical & Experimental Cardiology
    October 16-18, 2017 Chicago, USA

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version