Author(s): Powers JW, Mazilu JK, Lin S, McCabe ER
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Abstract Since the 1950s, scientists have attempted to characterize the relationship between diabetes mellitus (DM) and the hypothalamic-pituitary-adrenal (HPA) axis. Similar complications are seen in patients with diabetes and Cushing's syndrome, leading some to suggest that an underlying abnormality in the HPA axis may be responsible among those with DM. By inducing hyperglycemia in a zebrafish animal model, we show a direct correlation between glucose and cortisol levels. Copyright © 2010 Elsevier Inc. All rights reserved.
This article was published in Mol Genet Metab
and referenced in Journal of Diabetes & Metabolism