Author(s): Hafez M, Sharaf L, Abd elNabi SM
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Abstract The genetics of vitiligo has been studied in 150 probands and their families. A familial concentration of the disease has been demonstrated which supports the concept that hereditary factors contribute to the etiology of vitiligo. Segregation analysis was not consistent with inheritance at a single autosomal or x-linked locus. Further analysis suggested that vitiligo is determined by multifactorial inheritance. An estimate of heritability of liability was found to be 72.4\%, indicating that genetic factors play a significant role in the etiology.
This article was published in Acta Derm Venereol
and referenced in Journal of Addiction Research & Therapy