alexa The growing genetic links and the early onset of atopic diseases in children stress the unique role of the atopic march: a meta-analysis.
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Cantani A

Abstract Share this page

Abstract Allergic asthma and rhinitis, atopic dermatitis, urticaria and food allergy are genetic diseases present in infants and children. Several investigators have provided evidence for a genetic localization for atopy. Babies of atopic parents are at high risk of developing atopic diseases; however, the phenotypic expression of such diseases varies widely in that it can be very mild in some infants and children, severe and frustrating in many, even life-threatening in others, as well as also being common, disabling and chronic. A meta-analysis of all available studies on the age of onset of atopic march was carried out by selecting what appeared to be the most relevant articles in the literature rather than aiming for a comprehensive selection. It was found that in the first year of life, there is the onset of atopic dermatitis in 79.8\% (60.2-100\%) of babies, of cow's milk allergy in 72.7\%, egg allergy in 71\%, and fish allergy in 51.3\%. Asthma starts in the first year of life in 41.8\%, in the second in 49.3\%, and within the eighth year in 92.5\% of children. Allergic rhinitis begins in 35\% of babies in the first year of life, and in 59\% or 13-19\% in those aged 2-5 years. It seems therefore that up until now the role of pediatric allergy and immunology has been somewhat obscured, as can be witnessed by atopic march. Instead, pediatric allergy and immunology have a substantial, unmatched role, focusing on the early and often very early onset of atopy, which requires strategic intervention in the very first months of life or even before birth. As the main goal of modern medicine is prevention of chronic and severe diseases, the possibility of preventing such disorders in predisposed children has stimulated the imagination of researchers since the beginning of the century, when atopic diseases were not as common as they are now.
This article was published in J Investig Allergol Clin Immunol and referenced in Journal of Addiction Research & Therapy

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

agrifoodaquavet@omicsonline.com

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

clinical_biochem@omicsonline.com

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

business@omicsonline.com

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

chemicaleng_chemistry@omicsonline.com

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

environmentalsci@omicsonline.com

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

engineering@omicsonline.com

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

generalsci_healthcare@omicsonline.com

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

genetics_molbio@omicsonline.com

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

immuno_microbio@omicsonline.com

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

omics@omicsonline.com

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

materialsci@omicsonline.com

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

mathematics_physics@omicsonline.com

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

medical@omicsonline.com

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

neuro_psychology@omicsonline.com

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

pharma@omicsonline.com

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

social_politicalsci@omicsonline.com

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords