alexa The identification of vaginal Lactobacillus species and the demographic and microbiologic characteristics of women colonized by these species.
Infectious Diseases

Infectious Diseases

Journal of AIDS & Clinical Research

Author(s): Antonio MA, Hawes SE, Hillier SL, Antonio MA, Hawes SE, Hillier SL

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Abstract Lactobacillus acidophilus has been reported to be the predominant vaginal species. Vaginal lactobacilli isolated from 215 sexually active women were identified using whole-chromosomal DNA probes to 20 American Type Culture Collection Lactobacillus strains. Most women were colonized by L. crispatus (32\%), followed by L. jensenii (23\%), a previously undescribed species designated L. 1086V (15\%), L. gasseri (5\%), L. fermentum (0.3\%), L. oris (0.3\%), L. reuteri (0.3\%), L. ruminis (0.3\%), and L. vaginalis (0.3\%). H2O2 was produced by 95\% of L. crispatus and 94\% of L. jensenii isolates, compared with only 9\% of L. 1086V. Colonization by L. crispatus or L. jensenii was positively associated with being white (P<.001), age >/=20 years (P=.05), barrier contraceptive usage (P=.008), and lower frequency of bacterial vaginosis (P<.001) and gonorrhea (P=.03). L. crispatus and L. jensenii, not L. acidophilus, are the most common species of vaginal lactobacilli. This article was published in J Infect Dis and referenced in Journal of AIDS & Clinical Research

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