alexa The insulin-like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer.


Journal of Orthopedic Oncology

Author(s): Almeida A, Muleris M, Dutrillaux B, Malfoy B

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Abstract We report the amplification and overexpression of the IGFIR (insulin-like growth factor I receptor) gene in primary breast cancers with an amplification of band 15q26. The involvement of IGFIR, which may vary in frequency from 2-3\% in unselected tumor series to more than 10\% in breast cancers with hsr, may represent an important event in tumor progression.
This article was published in Genes Chromosomes Cancer and referenced in Journal of Orthopedic Oncology

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