alexa The multistep nature of cancer.


Surgery: Current Research

Author(s): Vogelstein B, Kinzler KW

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Abstract Cancer is a distinct type of genetic disease in which not one, but several, mutations are required. Each mutation drives a wave of cellular multiplication associated with gradual increases in tumor size, disorganization and malignancy. Three to six such mutations appear to be required to complete this process.
This article was published in Trends Genet and referenced in Surgery: Current Research

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