alexa The neo-adjuvant treatment in gastrointestinal stromal tumor.


Journal of Gastrointestinal & Digestive System

Author(s): Catania V, Consoli A, Cavallaro A, Liardo RL, Malaguarnera M

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Abstract Gastrointestinal Stromal Tumor (GIST) is a rare intra-abdominal tumor, characterized by a specific histological and immunohistochemical pattern. These tumors affect with higher frequency stomach and small bowel and occur at a median age of 60 years with a slight male predominance. An early stage of GIST often don't cause any symptoms, so most GISTs are diagnosed in later stages of the disease. We report a case of GIST diagnosed only with clinical data and positron emission tomography (PET). We demonstrate the usefulness of neoadjuvant treatment with Imatinib mesylate, a newly developed tyrosine kinase receptor inhibitor. The neoadjuvant treatment with Imatinib reduced the mass size and vascularization, making possible a surgical approach.
This article was published in Eur Rev Med Pharmacol Sci and referenced in Journal of Gastrointestinal & Digestive System

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