Author(s): McDonagh AJ, Messenger AG
Abstract Share this page
Abstract Knowledge of the disease mechanisms in alopecia areata is discussed in the light of progress in hair biology, immunology, and genetics. A disease model is presented incorporating polygenic determination of disease severity and susceptibility with largely unknown trigger factors responsible for initiating clinical disease expression. Experimental systems including animal models for alopecia areata offer new opportunities for investigation of alopecia areata and developing novel therapies.
This article was published in Dermatol Clin
and referenced in Hair Therapy & Transplantation