alexa The persistent risk of chronicity in recurrent episodes of nonbipolar major depressive disorder: a prospective follow-up.
Immunology

Immunology

Journal of Clinical & Cellular Immunology

Author(s): Keller MB, Lavori PW, Rice J, Coryell W, Hirschfeld RM

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Abstract The authors report on the course of illness in 101 patients who were in an episode (the "index episode") of major depressive disorder when they entered a clinical research study, recovered from that episode, and then relapsed into a new episode (the "first prospective episode") of the disorder. They found a 22\% probability that these patients' first prospective episode would last at least 1 year, similar to the 21\% rate of chronicity previously reported for the index episode. A long prior episode, older age, and low family income were found to predict chronicity in the first prospective episode. This article was published in Am J Psychiatry and referenced in Journal of Clinical & Cellular Immunology

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