Author(s): Keller MB, Lavori PW, Rice J, Coryell W, Hirschfeld RM
Abstract Share this page
Abstract The authors report on the course of illness in 101 patients who were in an episode (the "index episode") of major depressive disorder when they entered a clinical research study, recovered from that episode, and then relapsed into a new episode (the "first prospective episode") of the disorder. They found a 22\% probability that these patients' first prospective episode would last at least 1 year, similar to the 21\% rate of chronicity previously reported for the index episode. A long prior episode, older age, and low family income were found to predict chronicity in the first prospective episode.
This article was published in Am J Psychiatry
and referenced in Journal of Clinical & Cellular Immunology