Author(s): Tehrani FR, Simbar M, Tohidi M, Hosseinpanah F, Azizi F
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Abstract BACKGROUND: Despite the heavy burden and impact of the polycystic ovary syndrome (PCOS) in reproduction and public health, estimates regarding its prevalence at community levels are limited. We aimed to ascertain prevalence of PCOS in a community based sample using the National Institute of Health (NIH), the Rotterdam consensus (Rott.) and the Androgen Excess Society (AES) criteria. METHODS: Using the stratified, multistage probability cluster sampling method, 1126 women were randomly selected from among reproductive aged women of different geographic regions of Iran. PCOS were diagnosed using universal assessment of ultrasonographic parameters, hormonal profiles and clinical histories. RESULTS: The mean +/- SD of age of study population was 34.4 +/- 7.6 years. Estimated prevalence of idiopathic hirsutism was 10.9\% (95\% CI: 8.9-12.9\%); 8.3\% of women had only oligo/anovulation and 8.0\% had only polycystic ovaries. The prevalence of PCOS was 7.1\% (95\% CI: 5.4-8.8\%) using the NIH definition, 11.7\% (95\% CI: 9.5-13.7\%) by AES criteria and 14.6\% (95\% CI: 12.3-16.9\%) using the Rott definition. CONCLUSIONS: At community level, widespread screening of Rotterdam criteria will increase the estimated prevalence of PCOS over twofold. Establishing an explicit and contemporaneous method for definition and screening of each PCOS criteria has important investigational implications and increase the comparability of published research.
This article was published in Reprod Biol Endocrinol
and referenced in Journal of Diabetes & Metabolism