alexa The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined.


Journal of Blood & Lymph

Author(s): Swanson RS, Compton CC, Stewart AK, Bland KI

Abstract Share this page

Abstract BACKGROUND: T3N0 colon cancer is the target of many adjuvant studies. Very few studies have examined the relationship of the number of lymph nodes examined to the prognosis of this stage. We examined data from the National Cancer Data Base (NCDB) to determine whether the number of examined lymph nodes is prognostic for T3N0 colon cancer. METHODS: A total of 35,787 prospectively collected cases of T3N0 colon cancer that were surgically treated and pathologically reported from 1985 to 1991 to the NCDB as T3N0M0 were analyzed. RESULTS: The 5-year relative survival rate for T3N0M0 colon cancer varied from 64\% if 1 or 2 lymph nodes were examined to 86\% if > 25 lymph nodes were examined. Three strata of lymph nodes (1-7, 8-12, and > or = 13) distinguished significantly different observed 5-year survival rates. CONCLUSIONS: These results demonstrate that the prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. A minimum of 13 lymph nodes should be examined to label a T3 colon cancer as node negative. These data suggest that adjuvant trials for T3N0 colon cancer should stratify according to the number of lymph nodes examined.
This article was published in Ann Surg Oncol and referenced in Journal of Blood & Lymph

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version