alexa The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.
Immunology

Immunology

Journal of Clinical & Cellular Immunology

Author(s): Hanks SK, Quinn AM, Hunter T

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Abstract In recent years, members of the protein kinase family have been discovered at an accelerated pace. Most were first described, not through the traditional biochemical approach of protein purification and enzyme assay, but as putative protein kinase amino acid sequences deduced from the nucleotide sequences of molecularly cloned genes or complementary DNAs. Phylogenetic mapping of the conserved protein kinase catalytic domains can serve as a useful first step in the functional characterization of these newly identified family members.
This article was published in Science and referenced in Journal of Clinical & Cellular Immunology

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