alexa The relationship between the Young's modulus of the stratum corneum and age: a pilot study.


Journal of Aging Science

Author(s): Hara Y, Masuda Y, Hirao T, Yoshikawa N, Hara Y, Masuda Y, Hirao T, Yoshikawa N

Abstract Share this page

Abstract BACKGROUND/PURPOSE: The mechanical properties of the stratum corneum play an important role in protecting the body from external physical stimuli and excessive sensitivity. However, it is difficult to analyze these mechanical properties in vivo. To resolve this problem, we carried out a numerical analysis to calculate the Young's modulus of the stratum corneum. We then investigated the relationship between the Young's modulus of the stratum corneum and age. METHODS: We used a Cutometer(®) and a Dermal Torque Meter(®) for measuring skin mechanical parameters, and optical coherence tomography and an ultrasonic imaging system for measuring skin thickness. Based on these non-invasive results, liner elastic analysis was performed by the finite element method, and the Young's moduli of the stratum corneum and the dermis were calculated by solving an inverse problem. Using these techniques, we analyzed the correlation between the Young's modulus of the stratum corneum for the cheeks of seventy-eight Japanese women aged from 20 to 68 years. RESULTS: In the group study, the mean Young's moduli of the stratum corneum and dermis were calculated 1.993 MPa and 0.066 MPa, respectively. While carrying out individual analyses, there was a weak relationship between the Young's modulus of the stratum corneum and age (r = 0.337). CONCLUSION: We calculated the Young's modulus of the stratum corneum in vivo, with commercially available systems, and found that it is a weak correlation with age in this group of subjects. Future developments of our method would be beneficial in the characterization of facial skin aging and the validation of cosmetic and medical applications. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. This article was published in Skin Res Technol and referenced in Journal of Aging Science

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version