alexa The relationship of glycemic control to the outcomes of dental extractions.


Pharmaceutical Analytical Chemistry

Author(s): Aronovich S, Skope LW, Kelly JP, Kyriakides TC

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Abstract PURPOSE: The aim of this study was to determine whether glycemic control influences healing after tooth extractions. MATERIALS AND METHODS: We enrolled 115 diabetic patients who required dental extractions in this prospective observer-blinded study. Epithelialization of extraction sites was assessed relative to the patient's history, non-fasting blood glucose levels, and glycosylated hemoglobin levels. RESULTS: Of 115 patients, 78 had 1- and 2-week follow-up data. There was no statistically significant difference in the rate of postextraction epithelialization between diabetic patients based on preoperative blood glucose levels, hemoglobin A1c levels, or patient history. Only the size of the extraction site at days 0 and 7 was predictive of future epithelialization. CONCLUSIONS: Glycemic control did not influence postextraction healing in diabetic patients. Recommendations for management of the diabetic patient requiring extractions are discussed. Copyright © 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved. This article was published in J Oral Maxillofac Surg and referenced in Pharmaceutical Analytical Chemistry

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