Author(s): Christofori G, Semb H, Christofori G, Semb H
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Abstract E-cadherin-mediated cell-cell adhesion is lost during the development of most epithelial cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing loss of cell-cell adhesion, might also convey signals that actively induce tumour-cell invasion and metastasis.
This article was published in Trends Biochem Sci
and referenced in Journal of Cancer Science & Therapy