alexa The toxicology of chlorine.


Journal of Clinical Toxicology

Author(s): Winder C

Abstract Share this page

Abstract Chlorine is a reactive gas used by humanity for over two centuries. Exposure to chlorine has occurred in a number of situations, including as a chemical warfare agent, in industrial and domestic exposures, and as a result of accidents and spills. The toxicology of chlorine is related almost entirely to effects in the respiratory system. A consistent symptomology occurs in both animals and humans. This ranges from sensory irritation, to irritation and bronchospasm, to cellular changes to bronchioles and alveoli, to development of pulmonary disease. While full recovery from such injuries remains the most likely outcome, there is little doubt that permanent loss of function is possible in severe cases. In all industrial applications of chlorine, occupational exposures to chlorine should be controlled to at least the recommended exposure standard. However, a focus of activity on ensuring that excursions (such as leaks or "gassing" incidents) above these values do not occur is likely to be more beneficial. Treatment of chlorine exposure is essentially symptomatic, with the efficacy of some treatments (such as corticosteroid therapy) still not well established. Copyright 2001 Academic Press. This article was published in Environ Res and referenced in Journal of Clinical Toxicology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version