alexa The use of methotrexate for treatment of psoriasis in patients with HIV infection
Infectious Diseases

Infectious Diseases

Journal of Infectious Diseases & Therapy

Author(s): Maurer TA, Zackheim HS, Tuffanelli L, Berger TG

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The use of methotrexate (MTX) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease. We describe three HIV-infected patients who were given MTX for severe psoriatic arthritis. In two patients opportunistic infections did not develop. On the basis of survival data, it is not clear that use of MTX adversely affected the natural course of their HIV disease.

This article was published in Journal of the American Academy of Dermatology and referenced in Journal of Infectious Diseases & Therapy

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