Author(s): Culliford A, Daly J, Diamond B, Rubin M, Green PH
Abstract Share this page
Abstract BACKGROUND: Celiac disease may be complicated by symptoms that raise the suspicion of small-intestinal malignancy. The objective is to evaluate wireless capsule endoscopy (WCE) in complicated celiac disease. METHODS: This is a prospective study at a university referral center. There were 47 patients. The indications for WCE were abdominal pain (57\%), cancer surveillance (23\%), blood in the stool, or persistent iron deficiency (19\%). RESULTS: Findings were consistent with celiac disease in 87\%: atrophy (68\%), fissuring (62\%), and mosaic pattern (19\%), extending to the ileum in 34\%. Unexpected findings were ulceration in 45\% (n = 21), cancer (1), polyps (1), stricture (1), submucosal mass (1), ulcerated nodular mucosa (2), and intussusception (1) were seen in 60\%. CONCLUSIONS: WCE has a high yield in complicated celiac disease, by identifying mucosal abnormalities and by excluding adenocarcinoma.
This article was published in Gastrointest Endosc
and referenced in Journal of Gastrointestinal & Digestive System