alexa Thyroid gland: US screening in a random adult population.
Molecular Biology

Molecular Biology

Journal of Cytology & Histology

Author(s): Brander A, Viikinkoski P, Nickels J, Kivisaari L

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Abstract High-frequency ultrasound examination of the thyroid was performed in 253 subjects (130 women and 123 men; age range, 19-50 years) that were randomly selected from the population in an area of Finland where goiter is not endemic. Thyroid echo abnormalities were detected in 69 subjects (27.3\%). Prevalence of abnormalities increased with age, and women showed more lesions than did men in each of the 3 decades. The abnormality was solitary in 39 subjects (57\%), multiple in 15 (22\%), and diffuse in 15 (22\%). Of the 68 individual nodules, 48 (70\%) were smaller than 1 cm in diameter. Anechoic rounded nodules 1-5 mm in diameter were found in 28 subjects. Fine-needle aspiration biopsy was performed in 30 subjects. Cytologic examination revealed no unequivocal malignancies. In eight subjects (3.2\%) with a diffuse echo abnormality, cytologic evaluation indicated lymphocytic thyroiditis. It is concluded that the prevalence of small thyroid echo abnormalities in a randomly selected adult population is rather high, a fact that supports use of a conservative approach to these types of findings. This article was published in Radiology and referenced in Journal of Cytology & Histology

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