alexa TNF signaling in vascular endothelial cells.


Journal of Clinical & Cellular Immunology

Author(s): Madge LA, Pober JS

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Abstract Vascular endothelium is a major target of actions of the proinflammatory cytokine tumor necrosis factor (TNF). Increasingly, the intracellular pathways that are activated in response to TNF have been elucidated. Many of these pathways have proven to be cell type-specific, requiring that observations made in other cell types be confirmed or ruled out in endothelial cells (EC). In this review the authors will summarize the state of the field, emphasizing studies in cultured human EC. Copyright 2001 Academic Press. This article was published in Exp Mol Pathol and referenced in Journal of Clinical & Cellular Immunology

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