Author(s): Di Santo JP, Radtke F, Rodewald HR
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Abstract Recent studies have begun to unravel some of the molecular pathways that appear to control the processes of T cell determination in the earliest thymocyte precursors. In addition, the analyses of mouse mutants with an entirely alymphoid thymus have shed light on the developmental relationship of pro-T cells and thymic dendritic cells, revealing that development of thymocytes and thymic dendritic cells can be dissociated.
This article was published in Curr Opin Immunol
and referenced in Journal of Clinical & Cellular Immunology