alexa Too many referrals of low-risk women for BRCA1 2 genetic services by family physicians.


Journal of Antivirals & Antiretrovirals

Author(s): White DB, Bonham VL, Jenkins J, Stevens N, McBride CM

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Abstract The increasing availability and public awareness of BRCA1/2 genetic testing will increase women's self-referrals to genetic services. The objective of this study was to examine whether patient characteristics influence the referral decisions of family physicians when a patient requests BRCA1/2 genetic testing. Family physicians (n = 284) completed a Web-based survey in 2006 to assess their attitudes and practices related to the use of genetics in their clinical practice. Using a 2 x 2 x 2 factorial design, we tested the effects of a hypothetical patient's race, level of worry, and insurance status on the decisions of family physicians to refer her for BRCA1/2 testing. The patient was not appropriate for referral based on U.S. Preventive Services Task Force guidelines. No patient characteristics were associated with the family physicians' referral decisions. Although referral was not indicated, only 8\% did not refer to genetic services; 92\% referred for genetic services, and 50\% referred to genetic counseling. Family physicians regarded it unlikely that the patient carried a mutation, but 65\% of family physicians believed that if they refused to refer for genetic services it would harm their relationship with the patient. Despite scarce and costly genetic services, family physicians were likely to inappropriately refer a low-risk patient who requested BRCA1/2 testing. The implications of this inappropriate referral on women's screening behavior, genetic services, and health care costs are unknown. Clinicians and patients could benefit from education about the appropriate use of genetic services so that both are more comfortable with a decision against referral.
This article was published in Cancer Epidemiol Biomarkers Prev and referenced in Journal of Antivirals & Antiretrovirals

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