Author(s): Grillo HC
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Abstract This review discusses the need for tracheal replacement, distinct from resection with primary anastomosis, the requirements for replacement, and the many efforts over the past century to accomplish this goal experimentally and clinically. Approaches have included use of foreign materials, nonviable tissue, autogenous tissue, tissue engineering, and transplantation. Biological problems in each category are noted.
This article was published in Ann Thorac Surg
and referenced in Journal of Bioengineering & Biomedical Science