alexa Transpupillary thermotherapy (TTT) of occult choroidal neovascularization: A retrospective, noncomparative case series of fifty-seven eyes


Journal of Clinical & Experimental Ophthalmology

Author(s): Park CH, Duker JS, Mainster MA, Puliafito CA, Reichel E

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Purpose. To evaluate the efficacy of transpupillary thermotherapy (TTT) for the treatment of occult choroidal neovascularization. Methods. A retrospective, noncomparative case series of 57 eyes of 52 patients who presented with occult subfoveal CNV and were treated with TTT. Results. 83% of eyes were either stable (+/− one line) or showed improvement in visual acuity. 83% of eyes showed stabilization of their exudative process after one TTT treatment as evidenced by resorption of subretinal and/or intraretinal exudate or hemorrhage. Nine percent of eyes developed classic CNV during the mean follow-up time of ten months. Conclusions. TTT appears to stabilize the exudative process in eyes with occult CNV. A prospective, sham-controlled, randomized study (TTT4CNV Clinical Trial) is currently underway to directly compare TTT to the natural history of occult CNV

This article was published in Seminars in Ophthalmology and referenced in Journal of Clinical & Experimental Ophthalmology

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