Author(s): Bakke SA, Laursen SB
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Abstract A 66 year-old woman developed severe hypotension and bronchospasm as a result of disulfiram-ethanol reaction (DER). She presented with sudden onset of severe life-threatening symptoms. The clinical signs of DER were treated successfully and symptomatically with intravenous fluids, catecholamines, inhalations and benzodiazepines in the intensive care unit. Fomepizole, an alcohol dehydrogenase inhibitor, was advocated as a specific treatment for DER. This case highlights the potential danger of DER.
This article was published in Ugeskr Laeger
and referenced in Journal of Microbial & Biochemical Technology