Author(s): Speer J, Gehrke CW, Kuo KC, Waalkes TP, Borek E
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Abstract Seven breakdown products of tRNA were quantitated by high pressure liquid chromatography in urine and were related to the creatinine content. In the urine of 26 of 27 patients with 13 different malignancies, there was an elevation of one or more of these "markers." The levels of excretion vary approximately with the stage of the disease.
This article was published in Cancer
and referenced in Journal of Molecular Biomarkers & Diagnosis