alexa Tuberculosis of the breast masquerading as carcinoma: a study of 100 patients.
Clinical Research

Clinical Research

Journal of Clinical Case Reports

Author(s): Shinde SR, Chandawarkar RY, Deshmukh SP

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Abstract One hundred patients with tuberculous mastitis were referred to the Tata Memorial Hospital, a cancer center, with a clinical diagnosis of malignancy. This study identifies the possible causes of misdiagnosis and reviews the management of these patients. A lump in the breast with or without ulceration was the commonest presentation, the others being diffuse nodularity and multiple sinuses. Concomitant axillary lymph nodes were found in one-third of the patients. Tuberculosis lesions such as nodular mastitis, disseminated mastitis, and sclerosing lesions clinically mimicked a fibroadenoma, carcinoma, and fibrocystic mastitis depending on the mode of presentation. A young, multiparous, lactating woman with a lesion should arouse the suspicion of tuberculous mastitis, although pretherapeutic pathologic confirmation of a benign disease is mandatory. Mammography, fine-needle aspiration cytology, and excision biopsy for this purpose are successful in 14\%, 12\%, and 60\% of cases, respectively. Acid-fast bacilli were identified in 12\% patients. All patients received antituberculous chemotherapy, and 14\% patients required simple mastectomy, due to either lack of response to chemotherapy (10\%) or large painful, ulcerative lesions involving the entire breast (4\%). Axillary dissection was performed in only 8\% patients with large ulcerated axillary nodes. All patients, followed for a minimum of 2 years, were free of disease after therapy.
This article was published in World J Surg and referenced in Journal of Clinical Case Reports

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