alexa Tuberculosis of the thyroid gland: a clinicopathological profile of four cases and review of the literature.
Molecular Biology

Molecular Biology

Journal of Cytology & Histology

Author(s): Khan EM, Haque I, Pandey R, Mishra SK, Sharma AK

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Abstract Four cases of tuberculosis of the thyroid with different presentations including chronic sinus (following drainage of thyroid abscess), thyrotoxicosis, severe dysphagia clinically mimicking malignancy and euthyroid multinodular goitre are described. Except in the case presenting with chronic sinus (discharging acid-fast bacilli), the diagnosis was a pathological surprise (cytopathology in one and histopathology in two). Only in one case was there evidence of disease outside the cervical region. All cases showed multiple coalescing and caseating epitheloid cell granulomas along with giant cells, which are considered as diagnostic of tuberculous thyroiditis even if acid fast bacilli cannot be demonstrated. The literature is reviewed and the pathogenesis discussed.
This article was published in Aust N Z J Surg and referenced in Journal of Cytology & Histology

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