Author(s): Werbovetz KA
Abstract Share this page
Abstract Since tubulin is a known anticancer and anthelmintic drug target, the investigation of protozoal tubulin could lead to the development of new antiparasitic drugs. This review outlines the current state of knowledge concerning drug-mammalian tubulin interactions, the effects of antimicrotubule agents on parasites and parasite tubulin, and our current hypotheses regarding the development of selective ligands for protozoal tubulin as antiparasitic drug candidates.
This article was published in Mini Rev Med Chem
and referenced in Journal of Analytical & Bioanalytical Techniques