alexa Turning brain into blood: a hematopoietic fate adopted by adult neural stem cells in vivo.
Biomedical Sciences

Biomedical Sciences

Journal of Bioengineering & Biomedical Science

Author(s): Bjornson CR, Rietze RL, Reynolds BA, Magli MC, Vescovi AL

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Abstract Stem cells are found in various organs where they participate in tissue homeostasis by replacing differentiated cells lost to physiological turnover or injury. An investigation was performed to determine whether stem cells are restricted to produce specific cell types, namely, those from the tissue in which they reside. After transplantation into irradiated hosts, genetically labeled neural stem cells were found to produce a variety of blood cell types including myeloid and lymphoid cells as well as early hematopoietic cells. Thus, neural stem cells appear to have a wider differentiation potential than previously thought.
This article was published in Science and referenced in Journal of Bioengineering & Biomedical Science

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