alexa Type-2 diabetes and carotid stenosis: a proposal for a screening strategy in asymptomatic patients.


Journal of General Practice

Author(s): Lacroix P, Aboyans V, Criqui MH, Bertin F, Bouhamed T,

Abstract Share this page

Abstract The objective of this prospective observational study was to establish the prevalence of carotid atherosclerosis in an asymptomatic diabetic population and to determine predictive factors for a screening optimization. A total of 300 consecutive type-2 diabetic subjects (166 males, 134 females) underwent a physical examination and duplex carotid scanning. Patients with a recent cerebrovascular event (< or = 6 weeks) or previous carotid surgery were excluded. The prevalence of carotid stenosis > or = 60\% or occlusion was 4.7\%; the prevalence of carotid atherosclerosis was 68.3\%. Risk factors for stenosis > or = 60\% or occlusion were the presence of diabetic retinopathy (OR: 3.62; 95\% CI: 1.12-11.73), ankle-brachial index (ABI) <0.85 (OR: 3.94; 95\% CI: 1.21-12.84) and a personal history of neurological disorders (OR: 4.54; 95\% CI: 1.16-17.81). Being female was a protective factor (OR: 0.09; 95\% CI: 0.01-0.78). The two factors in the analysis limited to the male population were an ABI < 0.85 (OR: 3.66; 95\% CI: 1.04-12.84) and a personal history of coronary heart disease (OR: 3.34; 95\% CI: 1.01-11.01). If male diabetics without either of these two factors are excluded, the negative predictive value for carotid stenosis is 96.6\%. In conclusion, the prevalence of atherosclerotic carotid disease in diabetic patients is high. In these patients, the probability of finding >60\% stenosis is highest among men with a history of coronary heart disease or an ABI <0.85.
This article was published in Vasc Med and referenced in Journal of General Practice

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version