alexa Ultraviolet A riboflavin corneal cross-linking for infectious keratitis associated with corneal melts.


Journal of Microbial & Biochemical Technology

Author(s): Iseli HP, Thiel MA, Hafezi F, Kampmeier J, Seiler T

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Abstract PURPOSE: To evaluate the efficacy of ultraviolet-corneal cross-linking (CXL) for treating infectious melting keratitis. METHODS: Five patients with infectious keratitis associated with corneal melting were treated with CXL at the outpatient departments of the Institut für Refraktive und Ophthalmo-Chirurgie and the eye hospital at the University of Zurich. CXL was performed when the infection did not respond to systemic and topical antibiotic therapy. Follow-up after cross-linking ranged from 1 to 9 months. RESULTS: In all cases, the progression of corneal melting was halted after CXL treatment. Emergency keratoplasty was not necessary in any of the 5 cases presented. CONCLUSIONS: CXL is a promising option for treating patients with therapy-refractory infectious keratitis to avoid emergency keratoplasty. This article was published in Cornea and referenced in Journal of Microbial & Biochemical Technology

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