alexa Update on animal models for HIV research.
Immunology

Immunology

HIV: Current Research

Author(s): Haigwood NL, Haigwood NL

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Abstract Animal models for HIV research have been indispensible in fulfilling Koch's postulate and in exploring issues of viral infectivity and pathogenesis, sequence divergence, route(s) of acquisition, tissue distribution and tropism, immunogenicity and protection capacity of vaccine candidates, escape from adaptive immunity, and more. Did they fail to predict the efficacy of T-cell vaccines in humans? This article summarizes progress and status of models to inform and complement clinical work.
This article was published in Eur J Immunol and referenced in HIV: Current Research

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