alexa Update on Campylobacter jejuni vaccine development for preventing human campylobacteriosis.


Journal of Vaccines & Vaccination

Author(s): JagusztynKrynicka EK, aniewski P, Wyszyska A

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Abstract Campylobacteriosis constitutes a serious medical and socioeconomic problem worldwide. Rapidly increasing antibiotic resistance of bacterial strains compels us to develop alternative therapeutic strategies and to search for efficient immunoprophylactic methods. The vast majority of Campylobacter infections in developed countries occur as sporadic cases, mainly caused by eating undercooked Campylobacter-contaminated poultry. The most efficient strategy of decreasing the number of human Campylobacter infections is by implementing protective vaccinations for humans and/or chickens. Despite more than 10 years of research, an effective anti-Campylobacter vaccine has not been developed. This review highlights our increasing knowledge of Campylobacter interaction with host cells and focuses on recently published data describing the efficacy of anti-Campylobacter vaccine prototypes. This article was published in Expert Rev Vaccines and referenced in Journal of Vaccines & Vaccination

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