Author(s): Ciavarella D, Guiglia R, Campisi G, Di Cosola M, Di Liberto C,
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Abstract Severe gingival overgrowth is one of the most frequent side effects in renal transplant patients associated with assumption of cyclosporine A. Several associations with age, sex, dosage, duration of therapy or interval since transplantation have been hypothesized. The introduction of alternative immunosuppressant drugs have been suggested to permit better long-term transplant outcomes and a decrease in incidence of gingival overgrowth. The aim of the present paper is to summarize current knowledge regarding aetiology, pathogenesis and management of gingival overgrowth induced by Cyclosporine A.
This article was published in Med Oral Patol Oral Cir Bucal
and referenced in Dentistry