Author(s): Olsen L, Bowald S, Busch C, Carlsten J, Eriksson I
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Abstract Four centimeters of the canine urethra was replaced by a graft consisting of a polyglactin fiber mesh tube, coated with polyhydroxybutyric acid. Microscopic examination 8-12 months later showed almost complete regeneration of the urethral epithelium and the adjacent connective tissue. The neo-urethra was patent and there were no anastomotic strictures, nor was there any inflammatory reaction around the urethra. The validity of this concept in humans remains to be proved.
This article was published in Scand J Urol Nephrol
and referenced in Journal of Bioengineering & Biomedical Science