alexa Use of harmonic scalpel versus conventional haemostatic techniques in patients with Graves disease undergoing total thyroidectomy: a prospective randomised controlled trial. Langenbeck’s Arch Surg 393: 675-680.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Thyroid Disorders & Therapy

Author(s): P Hallgrimsson, L Lovn, J Westerdahl

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Introduction Thyrotoxicosis is often considered to be the most difficult thyroid operation because of the high vascularisation and the risk of bleeding. The conventional haemostatic technique in thyroidectomy today include knot tying and electrocoagulation. The introduction of the harmonic scalpel (HS) has led to further research if the use of the HS has any benefits in thyroid surgery. To our knowledge, no previous study has evaluated the HS dissection technique in a homogenous group of patients with Graves’ disease undergoing total thyroidectomy. Materials and methods Fifty-one patients (39 women and 12 men) with the pre-operative diagnosis of Graves’ disease treated at two endocrine centers were randomised to total thyroidectomy with the use of the HS or with conventional haemostatic techniques. Results Twenty-seven patients were randomised to the harmonic group and 24 to the conventional group. The operating time was shorter in the HS group (median, 121 min; range, 84–213 min) compared to the conventional group (median, 172 min; range, 66–268 min; p = 0.011). Conclusion The use of the HS was associated with a significant reduction in operating time compared to the use of the conventional haemostatic techniques in patients with Graves’ disease undergoing total thyroidectomy. Keywords ThyrotoxicosisHarmonic scalpelHaemostatic techniquesTotal thyroidectomy

This article was published in Langenbeck's Archives of Surgery and referenced in Journal of Thyroid Disorders & Therapy

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