alexa Use of streptomycin for precipitation and detection of proteinase K resistant prion protein (PrPsc) in biological samples.
Chemical Engineering

Chemical Engineering

Journal of Chromatography & Separation Techniques

Author(s): Moussa A, Coleman AW, Bencsik A, Leclere E, Perret F, , Moussa A, Coleman AW, Bencsik A, Leclere E, Perret F,

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Abstract The ability of streptomycin to form multimolecular aggregates with pathogenic prion proteins and their recovery by precipitation via a low-speed centrifugation step has been demonstrated; these novel properties of streptomycin make it a useful substance that increases the sensitivity of laboratory diagnostic techniques for prion infections in man and animals. This article was published in Chem Commun (Camb) and referenced in Journal of Chromatography & Separation Techniques

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