alexa Uterine mass and uterine blood volume in mice selected 21 generations for alternative criteria to increase litter size.
General Science

General Science

Biological Systems: Open Access

Author(s): Nielsen MK, Kittok RJ, Kochera Kirby YL

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Abstract Lines of mice, selected for 21 generations using alternative criteria to increase litter size, were evaluated for uterine mass and uterine blood volume to help explain differences in uterine capacity. For this study, mice were sampled from Generation 27, the sixth generation after relaxation of selection. Mice came from all four criteria of selection (LS = selection on number born to unaltered females; IX = selection on index of ovulation rate and ova success; UT = selection on uterine capacity; and LC = unselected control) in each of three replicates (a total of 12 lines). Measurement was at one of two stages, either 3 d or 6 d of gestation. Matings were at 10 wk of age, and a total of 508 mice (17 to 26 per line-day of pregnancy subclass) were measured. The mean of the three selected groups exceeded the control in uterine mass (P < .001), uterine blood volume (P < .002), uterine mass/body mass (P < .03), and uterine blood volume/body mass (P < .04) but not in uterine blood volume/uterine mass. Greater uterine mass and concomitantly greater uterine blood volume may have been partly responsible for greater uterine capacity resulting from LS, IX, and UT selections.
This article was published in J Anim Sci and referenced in Biological Systems: Open Access

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