alexa Vertical transmission of HIV-1 in the western region of the State of São Paulo.
Microbiology

Microbiology

Journal of Antivirals & Antiretrovirals

Author(s): Gonalves VL, Troiani C, Ribeiro AA, Spir PR, Gushiken EK,

Abstract Share this page

Abstract INTRODUCTION: This study aimed to determine the prevalence of vertical HIV-1 transmission in the western region of the State of São Paulo, Brazil. METHODS: The study analyzed the medical records of HIV-1-infected mothers and infant pairs living in the municipalities of São Paulo Regional Health Departments DRS II (Araçatuba) and DRS XI (Presidente Prudente). From March 2001 to March 2006, blood samples were collected and referred to the Molecular Biology Unit of the Adolfo Lutz Institute (ALI), Presidente Prudente. HIV-1-RNA viral load was determined by bDNA assay. RESULTS: The number of births (109/217, 50.2\%) and vertical HIV-1 transmissions (6/109, 5.5\%) that occurred in DRS II was similar to births (108/217, 49.8\%) and vertical transmissions (7/108, 6.5\%) in DRS XI (p > 0.05). Although 80\% (4/5) of the infected children were male in DRS II, while in DRS XI, 75\% (6/8) were female, no differences between sex regarding infected and noninfected children in the regions of Araçatuba and Presidente Prudente were verified. The overall vertical HIV-1 transmission rate was 6\%. No consistent reduction in the prevalence of vertical HIV-1 transmission occurred over the years. About 20\% of mothers did not know the HIV-1 status of their newborns eight months after delivery. CONCLUSIONS: In the present study, MTCT prevalence rates were about 70\% higher than those previously determined in the State of São Paulo, with noreduction throughout the period.Furthermore, a significant number of mothers did not know the HIV-status of their newborns eight months after delivery.
This article was published in Rev Soc Bras Med Trop and referenced in Journal of Antivirals & Antiretrovirals

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords