alexa Very late recurrences of leukemia: why does leukemia awake after many years of dormancy?
Microbiology

Microbiology

Journal of Antivirals & Antiretrovirals

Author(s): Norkin M, Uberti JP, Schiffer CA

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Abstract We report a heterogeneous group of very late recurrences of leukemia occurring more than 10 years after initial treatment including 2 cases of childhood acute lymphoblastic leukemia (ALL) which recurred after more than 20 years of remission, 2 cases of donor cell leukemia which developed more than 10 years after allograft for acute myeloid leukemia (AML) and high risk myelodysplastic syndrome (MDS) and 2 cases of chronic myeloid leukemia (CML) relapsing 13 and 17 years after allograft. Case descriptions are followed by a discussion regarding possible mechanisms leading to leukemia recurrence and a review of the literature. Copyright © 2010 Elsevier Ltd. All rights reserved. This article was published in Leuk Res and referenced in Journal of Antivirals & Antiretrovirals

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